Who wins: Even
From the counter table · Patch 7.2dSenna winsVayne wins
One of these champions is not usually played in this lane — treat the verdict as a rough guide.
- Even — No clear edge between Senna and Vayne — better play wins.
- The table is against you — Vayne is listed as a counter to Senna in this lane.
- From the enemy's side — Vayne's page lists Senna among its hardest matchups.
- Data from another lane — No row for this exact lane — verdict is based on their matchups elsewhere.
How to play it
- Don't chase
Vayne escapes faster than you — take farm and towers instead of running.
- Physical resistance
Vayne deals physical damage — Death's Dance as your 2nd or 3rd item.

When you are in danger
Items that answer Vayne
Grouped by why they work — hover or tap an item for its statsHow to beat Vayne
How to play as Senna
- Stay behind the frontline, Infinity Edge + attack speed second, kite divers
- Time CC on priority targets (ADC or Mid) to set up your team
Base stats by level (you / enemy)
■ Senna · ■ VayneLevel 1
- Health570 / 570
- Attack damage50 / 54
- Armor35 / 31
- Magic resistance30 / 30
- Attack speed0.63 / 0.83
- Movement speed340 / 335
Level 5
- Health1050 / 1050
- Attack damage50 / 66
- Armor53 / 49
- Magic resistance36 / 36
- Attack speed0.66 / 0.92
- Movement speed340 / 335
Level 15
- Health2250 / 2250
- Attack damage50 / 96
- Armor98 / 94
- Magic resistance50 / 50
- Attack speed0.73 / 1.14
- Movement speed340 / 335
The verdict is built from WildPick's curated counter table and the champions' kits — not from match win rates. Wild Rift has no public match API.




